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Memory health clinics—a first step to prevention
Author(s) -
Vellas Bruno,
GilletteGuyonnet Sophie,
Andrieu Sandrine
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2007.11.001
Subject(s) - disease , intervention (counseling) , european union , alzheimer's disease , medicine , clinical trial , disease prevention , gerontology , environmental health , psychiatry , business , pathology , international trade
A few years ago at the European Alzheimer's Disease Consortium–Alzheimer's Disease Cooperative Study meeting in Geneva we discussed with Leon Thal the possibility of building large multi‐domain primary preventive international trials for Alzheimer's disease (AD) both in North America and in the European Union. AD is a multifactorial phenomenon, and we will be more likely to succeed in preventive trials if we build a strategy using all potential protective factors to have the most potential effect instead of a simple and unique intervention. Leon Thal suggested that this could have a much bigger impact than all the drugs we might ever hope to develop. The main objective of this article is to present the rationale for multi‐domain preventive approaches.