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Exploring human/animal intersections: Converging lines of evidence in comparative models of aging
Author(s) -
Trojanowski John Q.,
Hendricks Joan C.,
Jedrziewski Kathryn,
Johnson F. Brad,
Michel Kathryn E.,
Hess Rebecka S.,
Cancro Michael P.,
Sleeper Meg M.,
Pignolo Robert,
Teff Karen L.,
Aguirre Gustavo D.,
Lee Virginia M.-Y.,
Lawler Dennis F.,
Pack Allan I.,
Davies Peter F.
Publication year - 2008
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2007.09.007
Subject(s) - translational research , human medicine , animal model , convergence (economics) , gerontology , medicine , psychology , pathology , economics , economic growth , traditional medicine , endocrinology
At a symposium convened on March 8, 2007 by the Institute on Aging at the University of Pennsylvania, researchers from the University's Schools of Medicine and Veterinary Medicine explored the convergence of aging research emerging from the two schools. Studies in human patients, animal models, and companion animals have revealed different but complementary aspects of the aging process, ranging from fundamental biologic aspects of aging to the treatment of age‐related diseases, both experimentally and in clinical practice. Participants concluded that neither animal nor human research alone will provide answers to most questions about the aging process. Instead, an optimal translational research model supports a bidirectional flow of information from animal models to clinical research.