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O2–02–07: Hippocampal diffusivity on DTI differ between amnestic and non‐amnestic MCI
Author(s) -
Kantarci Kejal,
Avula Ramesh,
Przybelski Scott,
Weigand Stephen,
Petersen Ronald C.,
Boeve Bradley F.,
Knopman David S.,
Smith Glenn E.,
Vemuri Prashanthi,
Jack Clifford R.
Publication year - 2007
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2007.04.041
Subject(s) - hippocampal formation , diffusion mri , fluid attenuated inversion recovery , medicine , cognitive impairment , nuclear medicine , fractional anisotropy , neuroscience , psychology , audiology , magnetic resonance imaging , radiology , disease
remain in clinical follow-up, and 9 of these have converted to AD (mean time-to-conversion 2.4 0.76 years). The mean activation magnitude among MCI-Converters was 0.63 and among MCI-Nonconverters -0.33 (Fig 2). There was a significant positive correlation between activation magnitude in the PMC and change in CDR-SOB score in the followup period. (Fig 3). Conclusion: Activation magnitude in the PMC, measured by fMRI, may serve as an important early diagnostic and prognostic marker to identify potential at-risk candidates for early intervention. O2-02-07 HIPPOCAMPAL DIFFUSIVITY ON DTI DIFFER BETWEEN AMNESTIC AND NON-AMNESTIC MCI