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P2–069: Nonhuman primate model for prediction of human Aβ effects. Targeting γ–secretase: Effects of enzyme inhibition vs. modulation of cleavage specificity on CSF and plasma Aβ in conscious rhesus monkeys
Author(s) -
Michener Maria S.,
Holahan Marie A.,
Gilberto David B.,
Sitko Gary R.,
Shearman Mark S.,
Harrison Tim,
Lewis Huw,
Sankaranarayanan Sethu,
Crouthamel Michelle,
Wu Guoxin,
Pietrak Beth L.,
Simon Adam J.,
Cook Jacquelynn J.
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.906
Subject(s) - cerebrospinal fluid , chemistry , pharmacology , cisterna magna , medicine