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P1–295: ADM.of exosomal c–cbl E3–ubiquitin ligase inhibited SRC–tyrosine kinase Fyn blocked phosphorylation of tau tyr18 and phosphorylation of MAP2c leading to inhibition of the neurogenerative process in the neurofibrillary tangles in the brains of rodents with Alzheimer's disease (AD)
Author(s) -
Giannios John,
Lambrinos Philip,
Alexandropoulos Nick
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.672
Subject(s) - fyn , phosphorylation , tyrosine kinase , microbiology and biotechnology , proto oncogene tyrosine protein kinase src , src family kinase , ubiquitin ligase , tyrosine phosphorylation , chemistry , kinase , tyrosine protein kinase csk , ubiquitin , biology , cancer research , signal transduction , biochemistry , sh3 domain , gene