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P4–244: Discovery of a novel series of notch–sparing γ–secretase inhibitors
Author(s) -
Harrison Boyd L.,
Kreft Anthony,
Aschmies Susan,
Atchison Kevin,
Cole Derek,
Ellingboe John,
Hauze Diane,
Hu Yun,
Huryn Donna,
Jin Mei,
Kubrak Dennis,
Lu Peimin,
Mann Charles,
Martone Robert,
Moore William,
Porte Alex,
Riddell David,
Sonnenberg-Reines June,
Stock Joseph,
Sun Shaiu-Ching,
Wagner Erik,
Woller Kevin,
Xu Zheng,
Zhou Hua,
Jacobsen Steven
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1984
Subject(s) - amyloid precursor protein secretase , notch signaling pathway , gamma secretase , pharmacology , ec50 , hydroxymethyl , lead compound , amyloid precursor protein , chemistry , alzheimer's disease , medicine , disease , in vitro , stereochemistry , biochemistry , signal transduction