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P3–397: Functional analysis of the protease active site domain of presenilin: Implications for γ–secretase substrate identification
Author(s) -
Pérez Revuelta Blanca I.,
Yamasaki Aya,
Eimer Stefan,
Okochi Masayasu,
Smialowska Agata,
Kaether Christoph,
Baumeister Ralf,
Haass Christian,
Steiner Harald
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1667
Subject(s) - presenilin , nicastrin , transmembrane domain , active site , notch signaling pathway , mutant , transmembrane protein , protein subunit , biology , microbiology and biotechnology , amyloid precursor protein , peptide sequence , amyloid precursor protein secretase , hek 293 cells , chemistry , biochemistry , signal transduction , amino acid , enzyme , receptor , alzheimer's disease , gene , medicine , disease , pathology