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P3–111: Triceps skinfold assessed at mid–life is associated inversely with dementia among survivors of a large cohort study
Author(s) -
Schnaider-Beeri Michal,
Davidson Michael,
Silverman Jeremy,
Goldbourt Uri
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1379
Subject(s) - dementia , medicine , cohort , anthropometry , demography , logistic regression , odds ratio , body mass index , cohort study , vascular dementia , gerontology , disease , sociology
2003 SC Behavioral Risk Factor Surveillance Survey to estimate risk factor rates (reported comparisons significant at p .05). We also estimated VaD prevalence using the SC Registry, with data from medical encounters, long-term care evaluations, the mental health system, adjacent states, vital records, and other sources, with one record per case. Data for 2003, with 6,600 individuals with VaD (other dementias excluded), were combined with US Census 2003 estimates to calculate prevalence. Chi-square tested Registry comparisons. Results: Although AAs and whites were equally likely to report cardiovascular diseases, AA rates were notably higher for diabetes (15.5% compared to 7.3%), hypertension (35.8%, 27.0%), obesity (37.8%, 20.4%), and physical inactivity (22.5%, 11.8%). AAs were less likely to have cholesterol checked or to eat fruits and vegetables, less likely to have Hemoglobin A1c testing for diabetes control, and had diabetes, stroke or myocardial infarction at younger ages. Results for VaD were consistent with these risks: At ages 85 , 10.1% of AA women had VaD, and 16.5% of AA men, compared with 4.2% and 5.1% for whites. Thus, rates for AAs were 2.4 times greater for women, 3.2 times for men (both p .0001). Analogous differences at younger ages were considerably larger, suggesting earlier onset for AAs. Conclusions: There is some evidence that AAs may have inherited risks for conditions involved in VaD; however, lifestyle is also a likely contributor. In the United States, rates of poor nutrition, inactivity, diabetes, hypertension, and obesity are increasing. Results imply that VaD rates may rise notably in the US, suggesting public health interventions to reduce behavioral risks for VaD.