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P3–104: Alpha–synucleinopathy in a multicenter population–based elderly cohort—cognitive function and ageing study (CFAS): Prevalence, staging and association with other pathologies
Author(s) -
Zaccai Julia,
Brayne Carol,
Ince Paul
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1372
Subject(s) - neuropathology , alpha synuclein , medicine , pathology , population , alpha (finance) , cohort , immunohistochemistry , parkinson's disease , disease , clinical psychology , construct validity , environmental health , psychometrics
differ significantly in age, age of onset, education, CDR and MMSE. Of the 73 FTD patients, 11 (15.1%) had FTD combined with motor neuron disease (MND). Of the 66 FTLD patients who had been asked about the family history, 12(12.4%) reported positive family history of dementia of unidentified etiology. Conclusions: Demographic features of our cohort were comparable to those of other countries. However the ratio of FTLD/AD was lower than it was in other studies. Regarding the subtypes of FTLD, compared with the data from UK and Japan, FTD was more common compared to the data of a study done in Japan but the proportion was similar to those of a study performed in UK.