Premium
P3–072: Mild cognitive impairment – the danger of basing the diagnosis on published normative groups
Author(s) -
Chertkow Howard M.,
Duong Anh,
Phillips Natalie,
Bergman Howard,
Babins Leonard,
Kelner Nora
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1339
Subject(s) - normative , psychology , population , neuropsychology , cohort , test (biology) , clinical psychology , neuropsychological test , cognition , developmental psychology , medicine , psychiatry , political science , pathology , paleontology , environmental health , law , biology
a screening test for cognitive impairment in both groups. MCI patients were categorized based on impairment in memory as well as verbal fluency. Results: STII showed good temporal test-retest reliability in all cognitive domains (r .84, p .0.01). Inter-item reliability showed that the set of items measured well the construct of cognitive impairments (Cronbach’s alpha .73, p .01)). Total STII scores correlate strongly with cognitive severity (r .71 vs. MMSE). STII characterized 58% of subjects as impaired and 42% as normal. Out of 88 patients, 92% had impaired memory; and of 63 normals, 30% had impaired memory, none had MCI, yet 9 subjects (50%) had isolated memory impairment. Furthermore, 10% of normals compared to 1% of patients showed impairment in verbal fluency. The STII items discriminated between patients with dementia and elderly controls (86% correctly classified). Conclusion: The STII is an internally consistent measure that provides a reliable, valid, and efficient screening for cognitive impairments in early dementia patients. Compared to the MMSE, STII seems to exhibit greater sensitivity in identifying subjects with MCI. STII requires minimal nonprofessional supervision and may be administered by an untrained person.