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P3–059: A preliminary study on the validation of Persian Clock Test in Iran
Author(s) -
Noroozian Maryam,
Ehtezazi Parinaz,
Seyedian Mazyar,
Ghassemzadeh Habibollah,
Nejat Saharnaz
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1326
Subject(s) - dementia , persian , functional illiteracy , test (biology) , receiver operating characteristic , neuropsychology , reliability (semiconductor) , population , neuropsychological test , neuropsychological assessment , psychology , medicine , cognition , statistics , mathematics , psychiatry , power (physics) , philosophy , law , linguistics , environmental health , biology , paleontology , quantum mechanics , political science , physics , disease
Background: One of the most important obstacles in the research on dementia and cognitive function in elderly population in developing country is “illiteracy.” Most of the neuropsychological tests which are currently used in this era have been designed for literate people. The Clock Drawing Test is one of the appropriate neuropsychological tests which can be used in the screening of dementia in illiterate people even though there are not enough studies on this test in the developing countries such as Iran. Objective(s): To propose an original evaluation and validation of the Persian Clock Test (PCT). Methods: We developed PCT after translation and back translation in four parts: drawing, completion, reading and clock setting. The study sample consisted of 250 healthy subjects aged over 50 years that were screened for probable cognitive impairment. Then we selected 181 subjects without dementia and administered PCT. Also 30 patients with dementia were assessed by this test. The score of each part of PCT and the total score of each subject was derived. After test-retest, sensitivity, specificity, cut off point, reliability and validity were computed. Also we analyzed the correlation between age, gender and the level of education with the scores of each subject. We evaluated the accuracy of four parts of PCT by Receiver Operating Characteristic Curve (ROC) analysis. Yuden’s Index was used for determination of cut off point. Results: The highest discriminatory power based on the area under the ROC curve was seen for the reading, clock setting and completion (0.9, 0.88, 0.82 and 0.72 respectively). The correlation between accuracy of reading, setting, completion and drawing was significant. The least correlation was found between drawing and other parts of PCT. The score of cut off point was 10/11 (total: 18). We found a significant correlation between the total score and the level of education. Conclusion: PCT is a valid tool and easy to conduct test which could be used for screening of dementia in the Iranian elderly population. The best discriminatory power of this test is seen in the reading, clock setting and completion part and the least power is seen in drawing test.