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P2–353: Automated volumetry of the amygdala and the hippocampus in Alzheimer's disease
Author(s) -
Bantumbakulu Albert-Romain Mukuna,
Chupin Marie,
Kinkingnehun Serge,
Sarazin Marie,
Hasboun Dominique,
Dormont Didier,
Garnero Line,
Dubois Bruno
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1193
Subject(s) - hippocampus , amygdala , atrophy , alzheimer's disease , magnetic resonance imaging , medicine , reliability (semiconductor) , nuclear medicine , pathology , neuroscience , psychology , disease , radiology , power (physics) , physics , quantum mechanics
lower threshold (see figure, voxel-level puncorrected 0.001), depositions were present in parietal areas (including the precuneus), inferior frontal gyri and middle and superior temporal cortex. Multiple linear regression analysis did not reveal any correlation between individual factor scores and anterior temporal amyloid deposition or global amyloid load. Conclusions: Bilateral anterior inferior temporal cortex is an area of predilection for amyloid deposition in early-stage AD. Within this population we did not find a clear correlation between neuritic amyloid deposition and cognitive dysfunction.