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P2–284: Flow artifacts in MR imaging for Alzheimer's detection and progression
Author(s) -
Sneller Beatrix,
Garde Ellen,
Atkinson David,
Batchelor Philip,
Fox Nick C.,
Hill Derek
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.1123
Subject(s) - artifact (error) , artificial intelligence , computer vision , electromagnetic coil , temporal lobe , intensity (physics) , computer science , physics , optics , medicine , quantum mechanics , psychiatry , epilepsy
no evidence for a difference in mean hippocampal atrophy rates between manual and fluid methods. Reliability for hippocampal atrophy rates derived by regional fluid registration (intraclass correlation coefficient (ICC): forward: left: 0.985; right: 0.988 and backward: left: 0.975; right: 0.989) was higher than for manual delineation (ICC: left: 0.798; right: 0.850). Conclusion: Regional fluid registration proved to be more reliable than manual delineation in assessing hippocampal atrophy rates, without sacrificing sensitivity to change. This method may be useful to quantify hippocampal volume change, especially in multi-center clinical trials, given the reduction in operator time and improved precision.