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O1–06–02: The design and synthesis of an efficacious BACE inhibitor
Author(s) -
McCarthy James R.,
Agejas Javier,
Bender David M.,
Broughton Howard,
Bueno Ana,
Dally Robert D.,
Durham Timothy,
Erickson Jon A.,
Espinosa Juan F.,
Gonzalez Rosario,
Hahn Patric J.,
Laigle Debra K.,
Kohn Todd J.,
May Patrick C.,
Rodriguez Juan R.,
Sanz Gema,
Shepherd Timothy A.,
Timm David,
Vidal Paloma,
Yang Hsiu-Chiung
Publication year - 2006
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2006.05.062
Subject(s) - chemistry , enzyme , amyloid precursor protein , enzyme inhibitor , rational design , stereoselectivity , limiting , cleavage (geology) , protease , protease inhibitor (pharmacology) , stereochemistry , amyloid precursor protein secretase , pharmacology , biochemistry , alzheimer's disease , disease , nanotechnology , biology , medicine , materials science , pathology , fracture (geology) , engineering , paleontology , catalysis , mechanical engineering , antiretroviral therapy , viral load , human immunodeficiency virus (hiv) , immunology