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[O2‐04‐07]: Attitudes, knowledge and intentions about genetic testing among relatives of Italian patients affected by familial dementia: Cross‐cultural comparison with Americans
Author(s) -
Binetti Giuliano,
Benussi Luisa,
Villa Aldo,
Roberts Scott,
Pasqualetti Patrizio,
Gigola Lara,
Barbiero Laura,
Green Robert C.,
Rossini Paolo M.,
Ghidoni Roberta
Publication year - 2005
Publication title -
alzheimer's and dementia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.713
H-Index - 118
eISSN - 1552-5279
pISSN - 1552-5260
DOI - 10.1016/j.jalz.2005.06.356
Subject(s) - dementia , genetic testing , frontotemporal dementia , psen1 , disease , psychology , clinical psychology , psychiatry , presenilin , population , perception , personality , family history , medicine , alzheimer's disease , social psychology , pathology , environmental health , radiology , neuroscience
of 27.1. Approximately 50% of the patients were self-referred, 30% were referred by general practitioners, and 20% by other physicians. 37% of the subjects had MCI-type 1, 16% MCI-type 2, 15% type 3, and 32% type 4. Isolated memory impairment was seen in 63% of the subjects, isolated impairment in a non-memory domain in 9%, impairments in multiple domains including memory in 22% of the subjects, impairments in multiple domains excluding memory in 6% of the subjects. Conclusions: One-third of the patients referred to a memory clinic had an MCI-type associated with an high risk for dementia, one-third an MCI-type associated with an intermediate risk for dementia, and one-third an MCI type associated with an low risk for dementia. In the majority of the cases the memory domain was impaired.