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Effective testing for pulmonary tuberculosis using Xpert MTB/RIF assay for stool specimens in immunocompetent Pakistani children
Author(s) -
Zahra Hasan,
Fehmina Arif,
Sadia Shakoor,
Aisha Mehnaz,
Fnu Alnoor,
Akbar Kanji,
Mussarat Ashraf,
Rumina Hasan
Publication year - 2016
Publication title -
international journal of mycobacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 20
eISSN - 2212-554X
pISSN - 2212-5531
DOI - 10.1016/j.ijmyco.2016.09.068
Subject(s) - pulmonary tuberculosis , medicine , genexpert mtb/rif , tuberculosis , virology , mycobacterium tuberculosis , pathology
Childhood tuberculosis (TB) is largely a paucibacillary disease and difficult to diagnose. It is difficult to obtain a sputum or gastric aspirate (GA) sample, and patients are often undiagnosed and treated empirically. Stool is a noninvasive specimen not usually used for TB testing in Pakistan. We investigated the value of Xpert MTB/RIF to diagnose Mycobacterium tuberculosis (MTB) in children with pulmonary TB cases, by performing comparative testing of GA and stool samples.

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