Fluoroquinolone consumption and -resistance trends in Mycobacterium tuberculosis and other respiratory pathogens: Ecological antibiotic pressure and consequences in Pakistan, 2009–2015 | Zendy

Sadia Shakoor | Zendy; Sabira Tahseen | Zendy; Kauser Jabeen | Zendy; Razia Fatima | Zendy; Faisal Malik | Zendy; Alamdar Hussain Rizvi | Zendy; Rumina Hasan | Zendy

Open Access

Fluoroquinolone consumption and -resistance trends in Mycobacterium tuberculosis and other respiratory pathogens: Ecological antibiotic pressure and consequences in Pakistan, 2009–2015

Author(s) -

Sadia Shakoor,

Sabira Tahseen,

Kauser Jabeen,

Razia Fatima,

Faisal Malik,

Alamdar Hussain Rizvi,

Rumina Hasan

Publication year - 2016

Publication title -

international journal of mycobacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 20

eISSN - 2212-554X

pISSN - 2212-5531

DOI - 10.1016/j.ijmyco.2016.07.008

Subject(s) - mycobacterium tuberculosis , tuberculosis , drug resistance , haemophilus influenzae , antibiotic resistance , population , shigella , medicine , multiple drug resistance , antibiotics , microbiology and biotechnology , biology , environmental health , bacteria , genetics , pathology , salmonella

Fluoroquinolones (FQs) are important anti-tuberculous drugs for the treatment of multidrug-resistant (MDR) tuberculosis. Resistance to FQs leads to fewer options for treatment of tuberculosis (TB), and infection with such strains may also require longer treatment duration. Trends of resistance in Mycobacterium tuberculosis (MTB) are indicators of MTB-resistance evolution. Drivers of such resistance need to be understood and studied to inform preventive strategies.

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