L-form transformation phenomenon in Mycobacterium tuberculosis associated with drug tolerance to ethambutol | Zendy

G. Slavchev | Zendy; Lilia Michailova | Zendy; Nadya Markova | Zendy

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L-form transformation phenomenon in Mycobacterium tuberculosis associated with drug tolerance to ethambutol

Author(s) -

G. Slavchev,

Lilia Michailova,

Nadya Markova

Publication year - 2016

Publication title -

international journal of mycobacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 20

eISSN - 2212-554X

pISSN - 2212-5531

DOI - 10.1016/j.ijmyco.2016.06.011

Subject(s) - ethambutol , mycobacterium tuberculosis , tuberculosis , population , microbiology and biotechnology , biology , mutation , cell wall , drug resistance , transformation (genetics) , bacteria , minimum inhibitory concentration , genetics , antibiotics , gene , streptomycin , medicine , pathology , environmental health

Cell wall-deficient bacterial forms (L-forms) may occur along with resistance to factors that trigger their appearance. It is of interest to study the relationship between the L-form transformation of Mycobacterium tuberculosis and the exhibition of drug tolerance to ethambutol (EMB), an inhibitor of cell wall synthesis.

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