Evaluation of the GenoType MTBDRplus assay for detection of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis isolates in central Ethiopia | Zendy

Zufan Bedewi Omer | Zendy; Yalemtsehay Mekonnen | Zendy; Adane Worku | Zendy; Aboma Zewde | Zendy; Girmay Medhin | Zendy; Temesgen Mohammed | Zendy; Rembert Pieper | Zendy; Gobena Ameni | Zendy

Open Access

Evaluation of the GenoType MTBDRplus assay for detection of rifampicin- and isoniazid-resistant Mycobacterium tuberculosis isolates in central Ethiopia

Author(s) -

Zufan Bedewi Omer,

Yalemtsehay Mekonnen,

Adane Worku,

Aboma Zewde,

Girmay Medhin,

Temesgen Mohammed,

Rembert Pieper,

Gobena Ameni

Publication year - 2016

Publication title -

international journal of mycobacteriology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.53

H-Index - 20

eISSN - 2212-554X

pISSN - 2212-5531

DOI - 10.1016/j.ijmyco.2016.06.005

Subject(s) - isoniazid , rifampicin , genotype , tuberculosis , mycobacterium tuberculosis , gold standard (test) , mycobacterium tuberculosis complex , medicine , virology , biology , microbiology and biotechnology , pathology , gene , genetics

Multidrug-resistant tuberculosis (MDR-TB) is growing globally and becoming a major challenge for national TB control programs. Therefore, rapid identification of MDR strains of Mycobacterium tuberculosis and monitoring their transmission could contribute significantly to the control of TB. The GenoType MTBDRplus assay has been recommended by the World Health Organization to identify rifampicin (RIF)- and isoniazid (INH)-resistant M. tuberculosis isolates. This study was carried out to evaluate the performance of the GenoType MTBDRplus assay for the detection of RIF- and INH-resistant M. tuberculosis isolates in central Ethiopia.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research