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Investigating structure–activity relationship and mechanism of action of antitubercular 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione [CD59]
Author(s) -
Ganesh Samala,
Shruti Singh Kakan,
Radhika Nallangi,
Parthiban Brindha Devi,
Jonnalagadda Padma Sridevi,
Shalini Saxena,
Perumal Yogeeswari,
Dharmarajan Sriram
Publication year - 2014
Publication title -
international journal of mycobacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 20
eISSN - 2212-554X
pISSN - 2212-5531
DOI - 10.1016/j.ijmyco.2014.02.006
Subject(s) - action (physics) , stereochemistry , mechanism of action , chemistry , mechanism (biology) , pharmacology , medicine , biochemistry , philosophy , physics , epistemology , in vitro , quantum mechanics
The objective of this study is to synthesize and evaluate 1-(4-chlorophenyl)-4-(4-hydroxy-3-methoxy-5-nitrobenzylidene) pyrazolidine-3,5-dione (CD59) analogues to establish structure-activity relationship and mechanism of action.

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