Performance indicators of fluorescence microscopy for sputum samples in pulmonary tuberculosis
Author(s) -
N Selvakumar,
Ashok Sunder,
M Gomathi Sekar,
C Ponnuraja,
Vanaja Kumar
Publication year - 2012
Publication title -
international journal of mycobacteriology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.53
H-Index - 20
eISSN - 2212-554X
pISSN - 2212-5531
DOI - 10.1016/j.ijmyco.2012.07.005
Subject(s) - sputum , tuberculosis , pulmonary tuberculosis , fluorescence microscope , medicine , microscopy , fluorescence , pathology , drug trial , clinical trial , optics , physics
To get insight into the sensitivity of fluorescence microscopy for diagnostic and follow-up sputum samples from pulmonary tuberculosis patients in clinical trials, the yield of smear positivity - among culture positive sputum samples - encountered in diagnostic and follow-up samples was retrospectively analyzed from the data available in a mycobacteriology laboratory in India. The sensitivity of fluorescence microscopy for diagnostic and follow-up samples respectively was found to be 94.3% and 60.7%. With these values as guidelines, the performance of fluorescence microscopy in the treatment of multi-drug resistant tuberculosis under DOTS plus program remains to be monitored and studied.
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