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A retrospective analysis of COVID-19 diagnosis results obtained by rapid antigen tests and RT-PCR: Implications for disease management
Author(s) -
Kiran Munne,
Venkanna Bhanothu,
Anjali Mayekar,
Shantanu Birje,
Vikrant M. Bhor,
Vainav Patel,
Smita D. Mahale,
Shailesh Pande
Publication year - 2021
Publication title -
indian journal of medical microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 48
eISSN - 1998-3646
pISSN - 0255-0857
DOI - 10.1016/j.ijmmb.2021.05.006
Subject(s) - asymptomatic , retrospective cohort study , medicine , covid-19 , disease , antigen , medical record , asymptomatic carrier , immunology , infectious disease (medical specialty)
There is a need for understanding and establishment of the most appropriate testing algorithm for COVID-19 diagnosis in asymptomatic high-risk groups. Here, we present a retrospective analysis of RT-PCR results obtained from 412 cases tested negative for coronavirus disease 2019 (COVID-19) by rapid antigen testing method. Among 178 (43.2%) asymptomatic individuals, 44.9% of the high risk contacts, 12.2% of police custody individuals, 22.22% of the pregnant women and 33.33% of individuals hospitalised for preoperative or other medical conditions showed RT-PCR positivity. Our results suggest a need for focussed and intensive (multi-modality) testing in groups at high risk for SARS-CoV-2 infection.

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