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Examination of placental three‐dimensional power Doppler indices and perinatal outcome in pregnancies complicated by intrauterine growth restriction
Author(s) -
Molnár András,
Surányi Andrea,
Nyári Tibor,
Németh Gábor,
Pál Attila
Publication year - 2015
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2014.10.035
Subject(s) - medicine , interquartile range , intrauterine growth restriction , obstetrics , pregnancy , prospective cohort study , outpatient clinic , gynecology , gestation , biology , genetics
Abstract Objective To examine placental vascularization using three‐dimensional power Doppler (3DPD) ultrasonography in pregnancies complicated by intrauterine growth restriction (IUGR). Methods The present prospective study was conducted at the University of Szeged (Szeged, Hungary) from February 2012 to March 2013. Women with a singleton pregnancy who attended the maternity outpatient ward in the second or third trimester were enrolled consecutively. Women were divided into two groups: those with a normal pregnancy and those with a pregnancy complicated by IUGR. Three 3DPD indices—vascularization index (VI), flow index (FI), and vascularization flow index (VFI)—were assessed. Results A total of 223 women were enrolled: 171 were in the control group and 52 in the IUGR group. Median VI was 3.7% (interquartile range [IQR] 3.2%–4.2%) in the IUGR group and 10.1% (IQR 8.6%–10.9%) in the control group ( P = 0.001). Median FI was 40.0 (IQR 39.7–42.5) in the IUGR group and 45.1 (IQR 44.1–53.1) in the control group ( P = 0.012). Median VFI was 2.2 (IQR 2.1–2.4) in the IUGR group and 4.8 (IQR 4.4–5.3) in the control group ( P < 0.001). Conclusion Placental vascularization was reduced in pregnancies complicated by IUGR.