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Risk factors for preterm premature rupture of membranes in Chinese women from urban cities
Author(s) -
Zhou Qiongjie,
Zhang Weiyuan,
Xu Huan,
Liang Huan,
Ruan Yan,
Zhou Shufeng,
Li Xiaotian
Publication year - 2014
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2014.06.020
Subject(s) - medicine , odds ratio , confidence interval , premature rupture of membranes , obstetrics , pregnancy , abortion , univariate analysis , population , multivariate analysis , demography , fetus , environmental health , biology , genetics , sociology
Objective To investigate the prevalence of preterm premature rupture of membranes (PPROM) in urban areas in China and examine the associated risk factors. Methods A population‐based, prospective study was undertaken in 14 cities in China between January 1, 2011, and January 31, 2012. Women were recruited at their first prenatal‐care visit, when maternal characteristics were recorded. Risk factors were analyzed by one‐way analysis of variance. Results Of 112 439 women included in analyses, 3077 (2.7%) had PPROM. Univariate analysis showed an increased risk of PPROM before 28 weeks of pregnancy in migrant women (odds ratio [OR] 2.25; 95% confidence interval [CI] 1.53–3.30; P < 0.001), in those with a history of recurrent induced abortions (OR 2.75; 95% CI 1.66–4.56; P < 0.001), and in those with a history of preterm birth (OR 3.90; 95% CI 0.77–19.61; P < 0.001). The associations were maintained in multivariate analysis ( P < 0.001). Conclusion Migration as a result of urbanization, high rates of induced abortion, and preterm birth are potential risk factors for PPROM in Chinese women.