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Visceral adiposity after tibolone use
Author(s) -
CarranzaLira Sebastián,
BárcenaJacobo Tomás D.,
SandovalBarragán Martha P.,
RamosLeón Julio C.
Publication year - 2011
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2011.05.030
Subject(s) - medicine , tibolone , menopause
Objective To evaluate the differences in visceral fat between women using tibolone and those not using tibolone. Methods Sixty‐five healthy postmenopausal women were included in the study: 26 who were taking tibolone (2.5 mg/day); and 39 who were not receiving tibolone treatment. Anthropometric measurements were performed, with subcutaneous and visceral fat measured via ultrasound. Differences between the groups were determined via Student t test. Results There were no significant differences in age ( P = 0.796), weight ( P = 0.256), height ( P = 0.456), body mass index ( P = 0.08), waist circumference ( P = 0.420), or waist–hip ratio ( P = 0.1) between the groups. Hip circumference was significantly lower in the study group than in the control group (97.7 ± 12.2 cm vs 103 ± 8.1 cm; P < 0.04). There were no significant differences between the groups in subcutaneous fat measurements ( P = 0.56). There were significantly lower visceral fat measurements (2.8 ± 1.1 cm vs 3.9 ± 1.6 cm; P < 0.004) and a significantly lower visceral fat–subcutaneous fat ratio (1.1 ± 0.3 vs 1.5 ± 0.7; P < 0.005) in the study group than in the control group. Conclusion Postmenopausal women who use tibolone have lower visceral fat measurements than do woman of similar age who do not use tibolone.