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Ovarian cancer during pregnancy
Author(s) -
Gezginç Kazım,
Karataylı Rengin,
Yazıcı Fatma,
Acar Ali,
Çelik Çetin,
Çapar Metin
Publication year - 2011
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2011.05.025
Subject(s) - medicine , pregnancy , germ cell tumors , ovarian cancer , ovarian tumor , dysgerminoma , hysterectomy , asymptomatic , stage (stratigraphy) , serous fluid , cancer , obstetrics , gynecology , surgery , ovary , chemotherapy , paleontology , genetics , biology
Objective To evaluate the clinical features, pregnancy outcome, and treatment of patients with ovarian cancer diagnosed during pregnancy. Methods The present study was a retrospective review of 11 cases of ovarian cancer detected during pregnancy. The women were treated and followed up at Selçuk University, Meram Faculty of Medicine, Konya, Turkey, during 2006–2010. Results Approximately half the patients were asymptomatic (5 [45.5%]) and diagnosed during cesarean delivery (6 [54.5%]). The histopathologic tumor categories comprised malignant epithelial ovarian tumor (4 [36.4%]), borderline tumor (4 [36.4%]), malignant germ cell tumor (2 [18.2%]), and sex cord stromal tumor (1 [9.1%]). Nine (81.8%) tumors were classified as stage I. Conservative surgery was performed in 10 (90.9%) patients. A patient with stage IIIC serous papillary adenocarcinoma underwent hysterectomy with bilateral salpingo‐oophorectomy. A patient with dysgerminoma in stage IV died on follow‐up. Three infants were born premature; they were followed up in the neonatal intensive care unit with satisfactory outcomes. Conclusion Early diagnosis and appropriate treatment are crucial for patients with ovarian cancer diagnosed during pregnancy. Tumor staging is possible during pregnancy, but the appropriateness of surgery needs to be considered carefully. Ideally, the treatment strategy should be discussed and structured on an individual basis.