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Laparoscopic salpingo‐oophorectomy for ovarian ablation in women with hormone‐sensitive breast cancer
Author(s) -
Haldar Krishnayan,
Giamougiannis Panagiotis,
Wilson Charles,
Crawford Robin
Publication year - 2011
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2010.12.013
Subject(s) - medicine , ovarian cancer , oophorectomy , gynecology , laparoscopy , breast cancer , general surgery , cancer , obstetrics , surgery , hysterectomy
Objective To evaluate institutional experiences regarding laparoscopic salpingo‐oophorectomy in breast cancer patients and to compare the technique with gonadotropin‐releasing hormone (GnRH) analogs among premenopausal women with hormone‐sensitive breast cancer. Methods Between 2004 and 2009, 103 women with breast cancer underwent laparoscopic salpingo‐oophorectomy at Addenbrooke's Hospital, Cambridge, UK. All relevant medical records—including reasons for salpingo‐oophorectomy, peri‐operative events, and subsequent follow‐up—were reviewed. Results In the study period, 3 (2.9%) women experienced a recurrence of breast cancer but none had primary peritoneal/ovarian cancer within a median follow‐up interval of 34 months (range, 0–70 months). No operative complications were noted among these women and all of them went home on the day of their operation. Conclusion Laparoscopic salpingo‐oophorectomy seems to be a safe, permanent, and cost‐effective method of ovarian ablation compared with the use of GnRH analogs. Salpingo‐oophorectomy also considerably reduces the risk of subsequent ovarian/fallopian tube malignancy in this high‐risk population.