Premium
Midtrimester abortion using vaginal misoprostol for women with three or more prior cesarean deliveries
Author(s) -
Fawzy Muhammad,
AbdelHady ElSaid
Publication year - 2010
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2010.02.008
Subject(s) - medicine , misoprostol , obstetrics , abortion , incomplete abortion , pregnancy , vagina , products of conception , gynecology , gestational age , surgery , biology , genetics
Objective To evaluate the safety and efficacy of vaginal misoprostol for second‐trimester abortion in women with 3 or more prior cesarean deliveries. Methods This study was conducted with 138 women who needed pregnancy termination between 13 and 26 gestational weeks, 31 with 3 or more previous cesarean deliveries and 107 with no uterine scars (the controls). Misoprostol was inserted in the vagina every 6 hours until regular contractions or products of conception appeared, a 200‐µg tablet for the first 24 hours and 2 tablets thereafter. The outcomes assessed were successful vaginal abortion, hemorrhage requiring blood transfusion, incomplete abortion, and uterine rupture. Results A vaginal abortion occurred in 28 women (90.3%) in the study group and 107 (100%) in the control group ( P = 0.01). There were no significant differences in the prevalence of the other assessed outcomes. Conclusion Vaginal misoprostol appears to be safe and acceptably effective for second‐trimester pregnancy termination in women with 3 or more previous cesarean deliveries.