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Anthropometric characteristics and success rates of oral or vaginal misoprostol for pregnancy termination in the first and second trimesters
Author(s) -
van Bogaert LouisJacques,
Misra Asha
Publication year - 2010
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2010.01.010
Subject(s) - misoprostol , medicine , obstetrics , pregnancy , abortion , anthropometry , medical abortion , prospective cohort study , gynecology , surgery , genetics , biology
Objective To assess the effect of anthropometric characteristics related to weight on medical pregnancy termination with misoprostol. Methods In this prospective cohort study, 454 women admitted for medical pregnancy termination in the first or second trimester took 400 µg of misoprostol sublingually plus 800 µg of misoprostol vaginally or orally. The regimen was readministered after 24 hours if there was no response or the abortion was incomplete, and surgical evacuation was done when needed. Linear regression was performed for possible correlations between the studied characteristics and treatment process and outcome. Results There was no correlation between the number of misoprostol administrations and any of the studied anthropometric characteristics. The numbers of both misoprostol administrations and surgical interventions were associated with oral administration. Conclusion The route of misoprostol administration, but not anthropometric characteristics related to weight, were found to be associated with the success of pregnancy termination with misoprostol.