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Aggressive characteristics of cervical cancer in young women in Taiwan
Author(s) -
Lau HeiYu,
Juang ChiMou,
Chen YiJen,
Twu NaeFang,
Yen MingShyen,
Chao KuanChong
Publication year - 2009
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2009.07.029
Subject(s) - medicine , parametrial , cervical cancer , stage (stratigraphy) , cervical carcinoma , retrospective cohort study , gynecology , cancer , basal cell , obstetrics , paleontology , biology
Objective To compare the characteristics and prognosis of cervical cancer in young women (under 30 years) with those of older women (over 30 years). Methods A retrospective study of 2443 patients diagnosed with FIGO stage IA–IIA cervical cancer who underwent surgical procedures between January 1983 and December 2007. Results Thirty patients (1.2%) were 30 years or younger. The proportion of non‐squamous cell carcinoma was higher in patients 30 years or younger compared with in patients over 30 years (14/30, 46.7% vs 10/30, 33.3%; P = 0.001). A higher rate of parametrial involvement was found in the younger group of patients compared with those over 30 years (10/30, 33.3% vs 289/2413, 12.0%; P = 0.001). Patients under 30 years had a higher rate of distant metastases compared with older patients (60% vs 49.7%; P = 0.036). Conclusions Non‐squamous histology, parametrial involvement, a higher rate of distant metastases, and poorer prognosis are more common in women aged 30 or younger with cervical cancer than in older women with the disease.