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Effect of cesarean delivery on the endometrium
Author(s) -
BenNagi Jara,
Walker Amy,
Jurkovic Davor,
Yazbek Joseph,
Aplin John D.
Publication year - 2009
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2009.02.019
Subject(s) - medicine , endometrium , pathophysiology , infiltration (hvac) , gynecology , andrology , urology , thermodynamics , physics
Objective To compare endometrial tissue samples from cesarean scar (CS) sites and from the posterior uterine wall to better understand the pathophysiology of implantation into a CS. Methods Endometrial samples were taken from both a CS site and the posterior wall in premenopausal women with CSs, and from the posterior wall in premenopausal women who had spontaneous vaginal deliveries (SVDs) only. Results In the secretory phase, there were significantly fewer leukocytes at CS sites than in the endometrium of women who had SVDs only ( P < 0.05). Significant differences in leukocytic infiltration and cell proliferation between the proliferative and secretory phases were only found in women who had SVDs only ( P < 0.05). Conclusion Leukocyte recruitment to the endometrium during the secretory phase may be affected by the presence of a CS.