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Repeat LEEP conization in patients with cervical intraepithelial neoplasia grade 3 and positive ectocervical margins
Author(s) -
Ayhan Ali,
Boynukalin F. Kubra,
Guven Suleyman,
Dogan N. Utku,
Esinler Ibrahim,
Usubutun Alp
Publication year - 2009
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2008.11.015
Subject(s) - medicine , cervical intraepithelial neoplasia , loop electrosurgical excision procedure , cervical conization , cervicitis , gynecology , cervical cancer , cancer
Objective To evaluate the effectiveness of repeat loop electrosurgical excision procedure (LEEP) conization in patients with cervical intraepithelial neoplasia (CIN) grade 3 and positive ectocervical margins. Method A retrospective study of 56 women who underwent repeat LEEP conization for CIN 3 and positive ectocervical margins. Results Final diagnosis after repeat LEEP conization revealed 6 women (10.7%) with microinvasive squamous cell carcinoma (Stage IA1); 1 (1.8%) with CIN 1; 1 (1.8%) with CIN 2; 21 (37.5%) with CIN 3; and 27 (48.2%) with chronic cervicitis. Ectocervical or endocervical margins were negative after repeat LEEP conization in the majority of women, except for 2 patients (3.6%) with CIN 3 and positive ectocervical margins. Recurrence rate for the median follow‐up time of 2 years was 6.1% (3 patients). Conclusion Repeat LEEP conization can reveal undiagnosed microinvasive cervical carcinoma in women with positive ectocervical margins.