Premium
Effectiveness and safety of loop electrosurgical excision procedure for cervical neoplasia in rural India
Author(s) -
Sankaranarayanan Rengaswamy,
Keshkar Vijay,
Kothari Ashok,
Kane Shubhada,
Fayette JeanMarie,
Shastri Surendra
Publication year - 2009
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2008.09.009
Subject(s) - medicine , loop electrosurgical excision procedure , colposcopy , cryotherapy , cervical intraepithelial neoplasia , cure rate , surgery , gynecology , obstetrics , cervical cancer , cancer
Abstract Objective To evaluate the effectiveness and safety of loop electrosurgical excision procedure (LEEP) to treat cervical intraepithelial neoplasia (CIN) in rural India. Method Women with CIN colposcopic features unsuitable for cryotherapy were treated with LEEP using a “see‐and‐treat” approach. Women with unsatisfactory colposcopy had diagnostic LEEP. Cure was defined as no clinical or histologic evidence of CIN at 1‐year follow‐up. Factors influencing cure rates were evaluated by χ 2 tests. Results Of the 1141 women who underwent LEEP (569 see‐and‐treat; 572 unsatisfactory colposcopy), 634 had histologically proven CIN. Of those, 489 reported for follow‐up and 459 (93.9%) had no evidence of disease. Cure rates were 98.1% for women with CIN 1, 93.6% for CIN 2, and 85.0% for CIN 3. Patients with CIN 2–3 had significantly lower cure rates. Conclusion Cure rates for LEEP provided by newly trained doctors in rural India were similar to those reported in the gynecological literature.