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Preoperative evaluation of pelvic masses with combined 18 F‐fluorodeoxyglucose positron emission tomography and computed tomography
Author(s) -
Yamamoto Yorito,
Oguri Hiroyoshi,
Yamada Ruriko,
Maeda Nagamasa,
Kohsaki Shino,
Fukaya Takao
Publication year - 2008
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2008.02.019
Subject(s) - medicine , positron emission tomography , radiology , magnetic resonance imaging , fluorodeoxyglucose , nuclear medicine , standardized uptake value , prospective cohort study , tomography , pathology
Objective: To prospectively evaluate the diagnostic value of combined 18 F‐fluorodeoxyglucose position emission tomography and computed tomography (FDG‐PET/CT) to discriminate malignant or borderline malignant tumors from benign pelvic masses. Methods: A prospective study of 30 women with suspected ovarian cancer who presented from July 2006 through August 2007. Selection was based on evidence from ultrasound, magnetic resonance imaging, and rising tumor marker levels. All patients underwent FDG‐PET/CT prior to standard debulking surgery for a pelvic mass. Results: The sensitivity and specificity of FDG‐PET/CT to detect malignant or borderline malignant pelvic tumors were 71.4% and 81.3%, respectively. The sensitivity and specificity of FDG‐PET/CT to detect ovarian cancer were 100% and 85.0%, respectively. The maximum standardized uptake value in borderline tumors was significantly lower compared with malignant tumors, but not significantly different compared with benign tumors. Conclusion: FDG‐PET/CT had a high diagnostic value in differentiating between malignant and benign tumors, and a low diagnostic value in differentiating between borderline malignant and benign tumors.