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Naproxen suppository for perineal pain after vaginal delivery
Author(s) -
Wilasrusmee Skuntala,
Chittachareon Apichart,
Jirasiritum Siriwan,
Srisangchai Prasong
Publication year - 2008
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2008.01.015
Subject(s) - medicine , suppository , naproxen , vaginal delivery , anesthesia , pregnancy , pharmacology , alternative medicine , pathology , biology , genetics
Objective To assess the effectiveness of rectal naproxen for reducing perineal pain after vaginal delivery. Methods A double‐blind randomized controlled trial of 142 post partum women randomly allocated to receive either naproxen (71 patients) or placebo (71 patients) suppositories. The first dose was given immediately after complete perineal suturing, while the second dose was given 6 hours post partum. The validated Thai short‐form McGill pain questionnaire was used to evaluate perineal pain at 0, 6, and 24 hours post partum. Pain scores were analyzed using the unpaired t test. Results Pain scores at 6 and 24 hours for women in the naproxen group were significantly lower compared with women in the placebo group (6.4 and 2.3 vs 18.4 and 5.5; P < 0.001). No side effects with naproxen were found. Conclusions Rectal naproxen is effective and safe for reducing perineal pain after vaginal delivery.