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Pelvic and para‐aortic lymphadenectomy in patients with endometrioid adenocarcinoma of the endometrium
Author(s) -
Geisler J.P.,
Linnemeier G.C.,
Manahan K.J.
Publication year - 2007
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2007.03.035
Subject(s) - medicine , lymphadenectomy , lymph node , lymph , endometrium , adenocarcinoma , urology , radiology , pathology , cancer
Background: The purpose is to determine the rate of lymph node metastases in women with endometrioid adenocarcinoma of the endometrium (EAE) undergoing systematic lymphadenectomy. Methods: Patients (349) underwent a complete pelvic and para‐aortic lymphadenectomy from caudal to the median circumflex to the level of the renal vessels. Results: Grade 1 tumors accounted for 32.7% of the tumors and 31.0% of the positive nodes, grade 2 accounted for 47.3% of the tumors (37.9% of positive nodes), and grade 3 accounted for 20.1% of the tumors and 31.0% of the positive nodes ( P > 0.05). Positive nodes were found in 15.8% of grade 1 tumors, 13.3% of grade 2 tumors and 25.7% of grade 3 tumors ( P > 0.05). Isolated para‐aortic involvement without pelvic nodal involvement occurred in 29% of patients with positive nodes. Conclusions: When complete lymphadenectomies are performed in EAE, positive lymph nodes (including isolated para‐aortic lymph nodes) are common in all grades.