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Intrapartum maternal glucose infusion and fetal acid‐base status
Author(s) -
Jamal A.,
Choobak N.,
Tabassomi F.
Publication year - 2007
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2007.01.016
Subject(s) - medicine , umbilical artery , saline , base excess , anesthesia , umbilical cord , hypercarbia , acid–base homeostasis , arterial ph , acidosis , pco2 , fetus , pregnancy , genetics , anatomy , biology
Objective : To compare the effects of an intrapartum infusion of a lactated Ringer solution or a glucose‐boosted saline solution on the acid‐base status of umbilical arterial blood. Method : In a prospective clinical trial 178 women in labor were randomized to receive intravenously either a lactated Ringer solution or a saline solution boosted with 5% glucose. Umbilical arterial blood was then assessed for acid‐base status. Results : There were significant differences between the lactated Ringer group and the glucose group in umbilical artery pH values (7.25 ± 0.07 vs. 7.28 ±0.06; P = 0.008), p CO 2 values (44.8 ± 5.6 mm Hg vs. 41.6 ± 4.1 mm Hg; P = 0.001), and base excess (− 7.3 ± 2.1 mEq/L vs. − 6.6 ± 1.8 mEq/L; P = 0.02). Conclusion : Intrapartum intravenous fluid containing a 5% glucose solution reduces umbilical cord acidemia and hypercarbia.