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Prognostic factors in node‐positive patients with stage IB‐IIB cervical cancer treated by radical hysterectomy and pelvic lymphadenectomy
Author(s) -
Kodama J.,
Seki N.,
Ojima Y.,
Nakamura K.,
Hongo A.,
Hiramatsu Y.
Publication year - 2006
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2006.02.012
Subject(s) - medicine , cervical cancer , radical hysterectomy , stage (stratigraphy) , chemoradiotherapy , histology , oncology , lymph node , population , multivariate analysis , hysterectomy , lymphadenectomy , cancer , surgery , paleontology , environmental health , biology
Objective The purpose of the present study was to identify prognostic factors in surgically treated patients with stage IB‐IIB cervical cancers, who also presented with positive pelvic nodes. Method The patient population consisted of 68 individuals presenting with stage IB‐IIB cervical cancers and with histologically proven pelvic lymph nodes. Result We found no association between the type of adjuvant therapy and patient outcome. Multivariate analysis revealed that non‐squamous histology was an independent prognostic factor for disease‐free and overall survival rates. In squamous cell carcinomas, the bilateral nature of the positive nodes was found to be a significant factor for disease‐free survival rates. In non‐squamous cell carcinomas, positive nodes of more than 2 cm in size were found to be a significant factor for disease‐free survival rates. Conclusion Non‐squamous histology was an independent prognostic factor and chemoradiotherapy did not improve the survival outcomes of the patients in this study population.