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Cervicography as an adjunctive test to visual inspection with acetic acid in cervical cancer detection screening
Author(s) -
BomfimHyppólito S.,
Santana Franco E.,
Gomes de Matos Meneses Franco R.,
Matos de Albuquerque C.,
Nunes G.C.
Publication year - 2006
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2005.09.016
Subject(s) - colposcopy , medicine , ascus (bryozoa) , cervical cancer screening , cervical cancer , cytology , biopsy , cervix , gynecology , loop electrosurgical excision procedure , predictive value , cancer , radiology , pathology , spore , biology , botany , ascospore
Objective : Validate Digital Cervicography as adjunctive cervical cancer screening test to VIA and Cytology. Method : Women (1292) were submitted to both cytological and VIA tests to obtain a sample of 301 positive VIA cases (23.3%) which have had the Digital Cervicography (DC) taken and evaluated. Just cases considered positive by DC (149/301 cases — 49.5%) and/or positive Pap smear tests were referred to colposcopy and biopsy whenever indicated. Results : Cervical smear was positive in 5.4%, including LGSIL (4%), HGSIL (1%) and one case of invasive cancer (0.4%), and 1.6% of ASCUS or AGUS). DC identified 81 positive cases (74 LGSIL; 5 HGSIL; 2 cancers). The sensitivity of cytology was 14.8%, and the DC was 100%. Corresponding specificities were 95.4% and 69.1%, respectively. The NPV and PPV for DC were 100% and 54.4%. Conclusion : DC increases sensitivity, specificity and positive predictive value of VIA, becoming a valid adjunctive screening test for cervical cancer in low resource settings.