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Effect of coffee intake on blood flow and maternal stress during the third trimester of pregnancy
Author(s) -
Tsubouchi H.,
Shimoya K.,
Hayashi S.,
Toda M.,
Morimoto K.,
Murata Y.
Publication year - 2006
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2005.09.011
Subject(s) - medicine , pregnancy , chromogranin a , fetus , blood flow , physiology , ingestion , obstetrics , endocrinology , genetics , immunohistochemistry , biology
Abstract Objective: To investigate the effects of maternal ingestion of an ordinary dose of coffee on maternal stress and placental and fetal blood circulation during the third trimester of pregnancy. Methods: We performed a Doppler blood flow analysis for 10 women in the third trimester of pregnancy before and after they drank a cup of coffee. Salivary samples were collected from the 10 pregnant women and 14 nonpregnant controls just before coffee intake and 30 min later. Salivary cortisol levels and chromogranin A titers were determined. Results: Coffee intake had no effect on maternal or fetal blood flow. Among the pregnant women, Salivary cortisol levels were significantly reduced after coffee intake but salivary chromogranin A concentration was not significantly different before and after coffee intake. Conclusion: The reduced salivary cortisol levels suggest that coffee intake decreases maternal stress during pregnancy.