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Risk of malignancy index in the preoperative evaluation of pelvic masses
Author(s) -
Obeidat B.R.,
Amarin Z.O.,
Latimer J.A.,
Crawford R.A.
Publication year - 2004
Publication title -
international journal of gynecology and obstetrics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.895
H-Index - 97
eISSN - 1879-3479
pISSN - 0020-7292
DOI - 10.1016/j.ijgo.2003.10.009
Subject(s) - medicine , malignancy , laparotomy , predictive value , ultrasound , radiology , retrospective cohort study , predictive value of tests , gynecology , surgery
Objectives : To assess the ability of a risk malignancy index (RMI) based on serum levels of CA 125, ultrasound findings, and menopausal status to discriminate between benign and malignant pelvic masses in a particular population. Methods : A retrospective study was conducted of 100 women with pelvic masses admitted for laparotomy. The sensitivity and specificity of serum levels of CA 125, ultrasound findings, and menopausal status were calculated both separately and combined into a RMI to diagnose malignancy. Results : The RMI was more accurate than any single criterion in diagnosing malignancy. Using a cut‐off level of 200 to indicate malignancy, the RMI gave a sensitivity of 90%, specificity of 89%, positive predictive value of 96%, and negative predictive value of 78%. Conclusion : The RMI is able to correctly discriminate between malignant and benign pelvic masses. It is a simple scoring system that can be introduced easily into clinical practice to facilitate the selection of patients who would benefit from primary surgery.