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IJDN Special issue on developmental brain injury
Author(s) -
Sizonenko S.V.
Publication year - 2015
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2015.07.002
Subject(s) - citation , associate editor , library science , psychology , medicine , computer science
Developmental brain injury remains a vast field of research with cerebral responses that are different according to the initial trigger, brain maturation at onset and intrinsic factors induced in repair and plasticity. Prematurity with acute hypoxia-ischemia and inflammation are the main source of developmental injury but poor intrauterine growth also leads to more subtle changes in the developmental programming of the brain. Further, medical interventions are not without effect on brain development. The brain facing injury reacts with several mechanisms that lead to acute damage and healing but also to long-term developmental changes due to its high capacity of plasticity. Better understanding of injury, reducing the initial damage and supporting the subsequent development is needed to protect the developing brain and reduce neurodevelopmental disabilities in these infants. The aim of this special issue is to expose recent advances in developmental brain injury through new experimental and imaging approaches, mechanisms of damage, analysis of anaesthetics effects, adaptation of the brain to adverse conditions and neuroprotection strategies.