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ISDN2014_0109: Digital nanodot gradients and adjustable reference surfaces to investigate axonal turning on substrate‐bound protein gradients
Author(s) -
Ricoult S.G.,
ThompsonSteckel G.,
Ongo G.,
Correia J.P.,
Kennedy T.E.,
Juncker D.
Publication year - 2015
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2015.04.089
Subject(s) - substrate (aquarium) , oceanography , geology
complexity, valence) including the age in which these scripts were acquired (i.e., “when did you first learn to perform this behaviour”). In two fMRI studies, participants processed both the procedural (“how”) and teleological (“why”) aspects of late-acquired and earlyacquired scripts. In both studies, and controlling for the various possible confounds and reaction times, processing late-acquired (vs. early-acquired) scripts activated the “default mode network”. These findings suggest that the default network is associated with mature cognitive processing, and thus join previous work in arguing against theories that ascribe very basic, early-acquired functions to the default network. We note three main interpretations of our data: (i) a relatively uncontroversial argument according to which the on-line processing of late-acquired (vs. early acquired) scripts recruited a different set of cognitive functions; (ii) a stronger claim according to which the differences in on-line patterns of activation stem from differences that existed at the time of script acquisition; (iii) a radical claim according to which age of script acquisition is one of the organizing principles of the cortex.