Epigenetic mechanisms regulating learning and long‐term memory | Zendy

Lipsky Robert H. | Zendy

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Epigenetic mechanisms regulating learning and long‐term memory

Author(s) -

Lipsky Robert H.

Publication year - 2013

Publication title -

international journal of developmental neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.761

H-Index - 88

eISSN - 1873-474X

pISSN - 0736-5748

DOI - 10.1016/j.ijdevneu.2012.10.110

Subject(s) - neuroscience , neurodegeneration , epigenetics , synaptic plasticity , cognition , neuroplasticity , cognitive decline , psychology , disease , balance (ability) , biology , medicine , dementia , receptor , pathology , gene , biochemistry

A balance between rapid, short lived, neuronal responses and prolonged ones fulfill the biochemical and cellular requirements for creating a molecular memory. I provide an overview of epigenetic mechanisms in the brain and discuss their impact on synaptic plasticity, cognitive functions, and discuss a recent example of how they can contribute to neurodegeneration and the cognitive decline associated with Alzheimer's disease.

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