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ISDN2012_0279: Cortical plasticity: Cell‐specific circuits and disorders of brain development
Author(s) -
Sur Mriganka
Publication year - 2012
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2012.10.100
Subject(s) - autism , citation , psychology , cognition , neuroscience , memory development , brain research , neuroplasticity , cognitive science , library science , computer science , cognitive development , psychiatry
neurogenesis, through the identification of novel genes involved in this process. Moreover, it constitutes a unique model linking cortical development and evolution, as the mouse and human pathways of corticogenesis display many similarities but also striking differences that may be related to species-specific developmental programmes. Finally, when grafted into the cerebral cortex of newborn mice, or lesioned cortex of adult mice, mouse and human ESC-derived cortical neurons develop complex and specific patterns of axonal and dendritic projections corresponding to endogenous cortical projections in vivo.