ISDN2012_0278: Fragile X syndrome and the amygdala

neurogenesis, through the identification of novel genes involved in this process. Moreover, it constitutes a unique model linking cortical development and evolution, as the mouse and human pathways of corticogenesis display many similarities but also striking differences that may be related to species-specific developmental programmes. Finally, when grafted into the cerebral cortex of newborn mice, or lesioned cortex of adult mice, mouse and human ESC-derived cortical neurons develop complex and specific patterns of axonal and dendritic projections corresponding to endogenous cortical projections in vivo.