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[P2.54]: Human evolution, human brain diseases
Author(s) -
Diaconeasa A.G.,
Spiru L.,
Turcu I.
Publication year - 2010
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2010.07.184
Subject(s) - library science , citation , political science , psychology , computer science
Our results show that MS doesnot produce any effect in object recognition capacity at these ages. Moreover, there are not significant differences in measured parameters of non-spatial memory neither sexes nor ages. However, spatial memory is apparently better in male than female adolescents. As time goes by an improvement on object location ability occurs only in females. As a result of that, the differences between sexes in young rats disappear in the adults. According to our results, only males are affected by maternal separation in a different manner depending on age. Therefore, MS impair spatial memory in adolescent male rats. As a direct consequence separated adolescent males has the same spatial memory than separated females. Nevertheless, MS improve spatial memory in adult males. The effect of MS in adults generates similar sexual differences showed in non-separated younger rats. In conclusion, we observed that maternal separation does not affect object recognition ability but it leads to long-term spatial memory changes, mainly in males, which are different owing to age.