[P1.90]: MARCKS‐associated signaling complexes regulate cell polarity during progenitor proliferation and neuronal differentiation | Zendy

Weimer J.M. | Zendy

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[P1.90]: MARCKS‐associated signaling complexes regulate cell polarity during progenitor proliferation and neuronal differentiation

Author(s) -

Weimer J.M.

Publication year - 2010

Publication title -

international journal of developmental neuroscience

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.761

H-Index - 88

eISSN - 1873-474X

pISSN - 0736-5748

DOI - 10.1016/j.ijdevneu.2010.07.130

Subject(s) - microbiology and biotechnology , polarity (international relations) , progenitor cell , progenitor , cell polarity , biology , neuroscience , neurogenesis , cell , stem cell , genetics

Concomitant with the downregulation of BMP signaling was a substantial increase in the expression of Smad7, an inhibitor of BMP signaling, and Bambi, a negative regulator of TGF-beta signaling, upon TSA and BMP2 treatment. Despite the striking discrepancy between the overall expression profiles in TSA and BMP2 treatment, some important genes are regulated similarly, supporting a connection between chromatin reorganization and BMP signaling.

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