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[P1.24]: Shifts in telomerase expression and activity during the transition from neurogenesis to gliogenesis in the developing spinal cord
Author(s) -
OlivosCisneros L.,
RamírezSantos J.,
GutiérrezOspina G.
Publication year - 2010
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2010.07.065
Subject(s) - gliogenesis , neurogenesis , humanities , art , psychology , biology , neuroscience , neural stem cell , genetics , stem cell
Fig. 1. Schematic of neuronal progenitor domains (green) in the ventral hindbrain and spinal cord. Both domains share a common genetic identity that is marked by expression of the transcription factors, Nkx2.2 and Ascl1. However, their neuronal outputs differ: ventral hindbrain progenitors generate VM and 5HT neurons, whereas corresponding spinal cord progenitors produce V3 neurons. The floor plate (FP) is shown for orientation.