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[P191]: The transcriptional regulation of glutamatergic pyramidal neurons by Neurogenin2
Author(s) -
Hand R.,
Polleux F.
Publication year - 2006
Publication title -
international journal of developmental neuroscience
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.761
H-Index - 88
eISSN - 1873-474X
pISSN - 0736-5748
DOI - 10.1016/j.ijdevneu.2006.09.251
Subject(s) - chapel , glutamatergic , citation , library science , computer science , neuroscience , psychology , history , art history , biology , genetics , glutamate receptor , receptor
PCNA in cells leaving the cell cycle decrease only about 30% within 24 h (Bravo and Macdonald-Bravo, 1987). Thus, weak Pax6/PCNAir periventricular cells could represent early postmitotic cells. The distribution of the periventricular intense Pax6ir cells in relation with some forebrain boundaries (alar-basal and diencephalon–mesencephalon boundaries, see abstract of Ferreiro-Galve et al.) is compatible with a role of Pax6 in the forebrain patterning. Moreover, the mediolateral distribution of Pax6ir cells could correspond with migratory streams related with axon guidance. In addition, in the forebrain of shark embryos (and juveniles) we have evidenced some Pax6ir cells also immunoreactive to TH or to GAD that represent differentiating neurons (Fig. 2).